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DeCS
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Descriptor English:
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Ataxins
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Descriptor Spanish:
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Ataxinas
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Descriptor Portuguese:
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Ataxinas
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Synonyms English:
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Ataxia Proteins, Spinocerebellar
Ataxin Proteins
Proteins, Ataxin
Proteins, Spinocerebellar Ataxia
Spinocerebellar Ataxia Proteins
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Tree Number:
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D12.776.631.069
D12.776.660.075
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Definition English:
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A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset. |
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See Related English:
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Spinocerebellar Ataxias
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History Note English:
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2016
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Allowable Qualifiers English:
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Record Number:
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56001
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Unique Identifier:
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D000067528
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Occurrence in VHL:
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Similar:
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DeCS
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